We usually have a navigation column
Nav1
Nav 2
Nav3
Nav4

Jabberwocky

`Twas brillig, and the slithy toves
  Did gyre and gimble in the wabe:
All mimsy were the borogoves,
  And the mome raths outgrabe.

The right margin is good for news, ads, photos, etc.. if you use a photo, the table cell will enlarge to match the with of the image.

I then start a new row spanning all 3 columns, then I close the cell, the row and then the entire table.